The influence of TNF-α inhibitors on radiological progression in ankylosing spondylitis

Kovalenko V.N.¹, Garmish O.O. ², Levchenko V.G.³, Romanovskiy A.V.¹

• ¹ГУ «ННЦ «Институт кардиологии им. Н.Д. Стражеско» НАМН Украины», Киев
• ²ГУ «ННЦ Институт кардиологии им. Н.Д. Стражеско» НАМН Украины», Киев
• ³Державна установа «Національний науковий центр «Інститут кардіології ім. М.Д. Стражеска» НАМН України», Київ

Summary. The article is devoted to the essential problem — if it is possible to stop, slowdown or prevent the «new bone formation» in ankylosing spondylitis. The results of evaluation of radiographic progression with 12 years follow-up in patients with ankylosing spondylitis were analyzed. mSASSS radiological scoring method for ankylosing spondylitis, relationships between structural and inflammatory changes of the spine as well as the influence of treatment on the ankylosing processes were reviewed. Clinical cases from own experience were described.