Kazimirko V.K. 1, Kozak I.А.2, Ivanitskaja L.M. 1, Silantjeva T.S. 1, Dubkova A.G. 1, Kutovyі V.V.3

Summary. Summary. The article presents the literature review devoted to the problem of calcium homeostasis. It contains material on the role of PTH and vitamin D in the regulation of calcium causes of hypo- and hypercalcemia. The role of osteotropic effects of magnesium and some trace elements is described. The importance of evidence concerning efficacy and safety of calcium and vitamin D for the prevention and treatment of patients with complex background of osteoporosis on the shortage of calcium intake in all age groups is emphasizes.

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