Oshlianska O.A.1, Artsymovych А.G.2

Summary. Relevance. Juvenile idiopathic arthritis (JIA), as one of the most common chronic childhood rheumatic diseases, always requires a thorough examination to identify lesions not only of the musculoskeletal system, but of all organs and systems that may be harmed as a result of prolonged exposure to pro-inflammatory cytokines. One of the systems that should be regularly monitored is the cardiovascular system (CVS), because it is precisely as a result of lesions of the CVS that fatalities in patients with rheumatic diseases most often occur. Purpose: to evaluate the effectiveness of using a signal-averaged 4th generation electrocardiogram (ECG) for early detection of CVS lesions in patients with JIA subvariants. Object: pediatric patients diagnosed with JIA. Materials and methods: a clinical, laboratory and instrumental examination of patients who were treated at the SI «IPOG of NAMS of Ukraine named after academician O.M. Lukyanova» with a diagnosis of JIA, which was performed according to the national protocol for the management of patients with JIA. In addition, a 4th gen-ECG was performed for children using the «Cardioplus P» software-hardware complex. Results: a comparative analysis of the data obtained using the standard 12-channel ECG and SHC «Cardioplus P», the calculated correlation of individual indicators of SHC «Cardioplus P» with clinically significant parameters of general clinical examinations. Conclusions: the use of SHC «Cardioplus P» allows to identify changes in various parameters from 12% to 100% of children with JIA, which is on average 40% more than the assessment of the standard 12-channel ECG. Also, carrying out this research method allows to highlight the leading types of disorders in the CVS with various sub-variants of the disease.

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