EVALUATION OF CARDIOVASCULAR SYSTEM INJURIES IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS USING 4th GENERATION ELECTROCARDIOGRAM
Summary. Relevance. Juvenile idiopathic arthritis (JIA), as one of the most common chronic childhood rheumatic diseases, always requires a thorough examination to identify lesions not only of the musculoskeletal system, but of all organs and systems that may be harmed as a result of prolonged exposure to pro-inflammatory cytokines. One of the systems that should be regularly monitored is the cardiovascular system (CVS), because it is precisely as a result of lesions of the CVS that fatalities in patients with rheumatic diseases most often occur. Purpose: to evaluate the effectiveness of using a signal-averaged 4th generation electrocardiogram (ECG) for early detection of CVS lesions in patients with JIA subvariants. Object: pediatric patients diagnosed with JIA. Materials and methods: a clinical, laboratory and instrumental examination of patients who were treated at the SI «IPOG of NAMS of Ukraine named after academician O.M. Lukyanova» with a diagnosis of JIA, which was performed according to the national protocol for the management of patients with JIA. In addition, a 4th gen-ECG was performed for children using the «Cardioplus P» software-hardware complex. Results: a comparative analysis of the data obtained using the standard 12-channel ECG and SHC «Cardioplus P», the calculated correlation of individual indicators of SHC «Cardioplus P» with clinically significant parameters of general clinical examinations. Conclusions: the use of SHC «Cardioplus P» allows to identify changes in various parameters from 12% to 100% of children with JIA, which is on average 40% more than the assessment of the standard 12-channel ECG. Also, carrying out this research method allows to highlight the leading types of disorders in the CVS with various sub-variants of the disease.
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