Traditional cardiovascular risk factors occurrence among female patients with rheumatoid arthritis

Garmish O.O. ¹, Mitchenko O.I. ², Levchenko V.G.³

• ¹SI «NSC «Institute of Cardiology M.D. Strazhesko» NAMS of Ukraine», Kyiv
• ²Державна установа «ННЦ «Інститут кардіології ім. М.Д. Стражеска» НАМН України»
• ³Державна установа «Національний науковий центр «Інститут кардіології ім. М.Д. Стражеска» НАМН України», Київ

Summary. The aim of the research was determination of cardiovascular risk factors occurrence among women with rheumatoid arthritis (RA). Investigation of 105 patients with RA was performed according to protocol. Smoking, ischemic heart failure and diabetes mellitus were registered in anamnesis. Systo­lic blood pressure, diastolic blood pressure and body mass index (BMI) were measured according to standard methods, lipid index was determined based on total cholesterol, high density lipoprotein, low density lipoprotein (LDL) and triglycerides (TG) count. Biochemistry analysis was performed using venous blood serum. The most widespread cardiovascular risk factors among the diagnosed patients with RA are LDL >1.7 mmol/l, TG >3.0 mmol/l, hypercholesterolemia (total cholesterol >5.0 mmol/l), age >55, increase of BMI. Arterial hypertension occurrence increased in women with menopause and was registered among 95.8% patients whereas its quantitative indices were proved to be higher in patients with increased body weight and duration of RA for more than 5 years. Occurrence of hypercholesterolemia and family anamnesis of Coronary Heart Disease (CHD) were proved to be more frequent in postmenopause patients and patients with RA duration for more than 5 years. Diabetes mellitus and BMI >25 kg/m2 were seen more frequently in this group of patients.