Bombela V.O., Shapoval І.І., Shvets L.V., Perebetyuk L.S., Andrushko І.І., Stanislavchuk М.А.

Summary. Pain is a leading cause of disability in patients with rheumatic diseases, which significantly affects the functional capabilities of such patients and significantly worsens their quality of life. A reduction in pain intensity is one of the important components of treatment, which depends both on the localization and intensity of pain, and on the mechanisms of its formation. Recent evidence suggests that in patients with inflammatory joint diseases, in addition to nociceptive and neuropathic pain, general pain perception may be associated with central sensitization. Features of central sensitisation have been documented in various pain conditions common in rheumatology practice, including fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, lower back pain, etc. The article presents the latest data on the features of central sensitization in rheumatic diseases.

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