Smiyan S.I., Gusak S.R.

Summary. Relevance. Acute septic arthritis in rheumatology is an urgent clinical case. Bacterial replication in the joint’s space and this inflammatory process can lead to rapid local destruction of the joint and the development of systemic infection. The purpose of the study: to summarise and analyse complex information regarding septic arthritis. Materials and methods. A review of modern literature on septic arthritis based on scientometric databases: MEDLINE/PubMed, Cochrane Library, Google Scholar. Results and discussion. Background joint pathology like rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriatic arthritis, hemarthrosis and joint replacement therapy contributes to an increased risk of septic arthritis, especially in case of intraarticular steroids injections, using of cytotoxic immunosuppressants and biological therapy. The leading syndrome in septic arthritis is mono-, oligoarthritic with a predominant involvement of large joints (knee, ankle) with signs of typical inflammation (edema, local fever, redness, significant pain on palpation and movement). Conclusions. Timely diagnosis of septic arthritis and appropriate targeted therapy is extremely important to reduce morbidity and mortality associated with this disease.

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