Study of quality of life parameters and tolerance to physical activity in patients with myocarditis during 12 months observation
Summary. Aim. Complex assessment of the quality of life and tolerance of physical exercise in patients with myocarditis and a reduced LV ejection fraction within 12 months observation. Results. The distance of the 6-minute test was minimal in the first month from the beginning of disease and amounted to 228.3±17.2 m, after 12 months of the observation, its value significantly increased and averaged 382.4±16.1 m (p<0.01). After 12 months of follow-up in the first group, the distance traveled in 6 min. was 14,2% (p<0.05) higher than in the 2-nd group, the magnitude of the LVEF in patients of the 1 st group increased by 27.8% within 12 months (p<0.01). In patients of the 2-nd group there was no significant increase in LVEF after 12 months of observation. The MLHFQ score was the highest in the first month of the onset of the disease. After 12 months the general BINR index as well as its components in the physical and emotional spheres decreased by 19.7% (p<0.01), 37.5% (p<0.005) and 18.5 (p<0.05), respectively, in patients 1 group, and by 10.5% (p>0.05), 12% (p<0.05), and 9.4% (p>0.05), respectively, in the patients of the 2 nd group, and in patients The 2-nd group of physical index LQ was 23.5% (p<0.01) higher, while in the emotional sphere no significant differences in the values of these indicators were found. Conclusions. Patients who had a LVEF ≤40% after 12 months of observation had a significantly lower exercise tolerance for the 6-minute walk test and a higher MLHFQ score in the physical and emotional spheres compared to the group of patients where the magnitude The LVEF was >40%. In patients with myocarditis after 12 months of follow-up, the magnitude of LVEF, EDV index and 6-minute test, the emotional distance of the 6-minute test was the greatest impact on physical index of life quality.
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