Number№83 (1) 2021

CLINICAL CASE OF PYODERMA GANGRENOSUM DEVELOPMENT IN PATIENTS WITH SJOGREN’S DISEASE

Tripolka S.A.1, Golovach I.Yu.2

Summary. The article presents a description of the clinical case of development of a rare manifestation of autoimmune diseases — gangrenous pyoderma in a patient with Sjogren’s disease. Initially, the patient was diagnosed with an erroneous diagnosis, which led to the appointment of antibiotics and vascular therapy with synthetic analogues of prostaglandins without clinical effect. The diagnosis made by a rheumatologist and the use of pulse therapy with methylprednisolone and methotrexate contributed to the significant positive dynamics and healing of the affected areas. The diagnostic criteria of gangrenous pyoderma and the detailed picture of the classical variant of the disease are presented in the article. A critical analysis of the patient’s curation was also conducted, and the reasons for the untimely diagnosis were discussed. Clinical evaluation of a patient with suspected gangrenous pyoderma should include careful collection of anamnesis and physical examination. The diagnosis of gangrenous pyoderma is characterized by rapid development of lesion, initial lesion in the form of papules, pustules or vesicles; pain proportional to the lesion area; the history of previous trauma and the history of autoimmune diseases related to gangrenous pyoderma.

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