EFFICACYOF STANDARD TREATMENT IN RHEUMATOID ARTHRITIS PATIENTS DEPENDED ON LEVEL OF LEPTIN

Stygar М.V. , Stanislavchuk М.А.

Summary. Summary. 78 females with rheumatoid arthritis (RA) aged 50.2±12.1 years and 30 healthy control group representative by ageand sex were includedin study. The standard treatment efficiency depending on the blood leptin level was studied. A significant increase in leptin blood levels in RA patients was found. In patients with high levels of leptin (above 32.5 ng/ml)such treatment efficiency indicators as the dynamics of painful and swollen joints count, ESR and DAS28 was the lowest. At the same time the maximum dynamic of the studied parameters after 12 and 24 weeks was observed in the patients with low leptin levels (

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