Clinical and immunological features of uveitis in rheumatic diseases

Kondratyuk V.E.¹, Sidorova M.V.², Ivashkivskii O.I.³, Beyko H.V.⁴, Kovhanych T.O.⁵

• ¹O.O. Bohomolets National Medical University, Kyiv
• ²Київська обласна клінічна лікарня, Київ
• ³Alexander Clinical Hospital, Kyiv
• ⁴O.O. Bohomolets National Medical University, Kyiv
• ⁵Олександрівська клінічна лікарня, Київ

Summary. Summary. The article provides an overview of publications on the problem of uveitis in different types of rheumatic diseases. The problems of epidemiology, classification, characteristics of pathogenesis, clinical manifestations, diagnosis of uveitis and its complications are represented in this article. The degree of inflammation varies from iridocyclitis to panuveitis and localization of the uveitis depends on the nosology of rheumatic diseases. For seronegative spondyloarthritis choroidal lesion is typical. Lesions of the eye may precede the development of spondylitis and be absent in the case of its high activity and a significant limitation. In anterior uveitis patients worried about the pain, photophobia, redness of the eye and loss of vision. Its complications are: subatrophy and ftizys of the eye, acute attack of glaucoma, secondary cataract. Posterior uveitis is painless, with no external signs of inflammation in the eye. Complications of the latter are: decreased visual acuity, cystic macular oedema, swelling of the optic nerve, chorioretinal atrophy, destruction and fibrosis of the vitreous, retinal detachment, subatrophy of the eyeball. The combination of scleritis with uveitis can lead to the development of necrotizing scleritis and peripheral corneal ulcers.