Ferrous sulfate effects on the state of prooxidant-antioxidant system in patients with iron deficiency anemia and of rheumatoid arthritis

Vatutin M.T. ¹, Smyrnova G.S. ¹, Shevelok A.N.¹, Komarova E.B. ²

• ¹Донецкий национальный медицинский университет им. Максима Горького
• ²ГУ «Луганский государственный медицинский университет»

Summary. Summary. This study has compared the levels of malonyl dialdehyde and catalase in patients suffering from rheumatoid arthritis and iron deficiency anemia before and after treatment with oral ferrous sulfate. It is concluded that the normalization of hemoglobin under the influence of ferrous sulfate associated with reduced activity of lipid peroxidation, and their lack of effectiveness is associated with preservation of prooxidant-antioxidant imbalance.